A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial
Background: Veterans living with HIV have up to twice the risk of atherosclerotic cardiovascular disease (ASCVD) compared to those without HIV. Objective: Our study seeks to test a non-physician led virtual self-management implementation strategy to reduce ASCVD risk among people living with HIV (PW...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | HIV Research & Clinical Practice |
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| Online Access: | http://dx.doi.org/10.1080/25787489.2023.2261747 |
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| author | Lewis Musoke Hayden B. Bosworth Christina Dickson Pamela Gentry Elizabeth Strawbridge Soumya Subramaniam Jennifer Gierisch Valerie Smith Sandra Woolson John Pura Willington Amutuhaire Susanna Naggie Julie Schexnayder Karen Hall Chris T. Longenecker Nadine M. Harris Chantrice Rogers Puja Van Epps for V-EXTRA-CVD Group |
| author_facet | Lewis Musoke Hayden B. Bosworth Christina Dickson Pamela Gentry Elizabeth Strawbridge Soumya Subramaniam Jennifer Gierisch Valerie Smith Sandra Woolson John Pura Willington Amutuhaire Susanna Naggie Julie Schexnayder Karen Hall Chris T. Longenecker Nadine M. Harris Chantrice Rogers Puja Van Epps for V-EXTRA-CVD Group |
| author_sort | Lewis Musoke |
| collection | DOAJ |
| description | Background: Veterans living with HIV have up to twice the risk of atherosclerotic cardiovascular disease (ASCVD) compared to those without HIV. Objective: Our study seeks to test a non-physician led virtual self-management implementation strategy to reduce ASCVD risk among people living with HIV (PWH). We aim to conduct a randomized control trial among PWH (n = 300) with a diagnosis of hypertension (HTN) who are enrolled in Veterans Health Administration (VHA) clinics, on suppressive antiretroviral therapy (ART), randomized 1:1 to intervention vs. education control for a 12-month duration. Methods: Using human centered design approach, we have adapted a previous 5-component telehealth focused, non-physician led intervention to a Veteran population. The education control arm receives enhanced education in addition to usual care. The primary outcome is 6 mmHg reduction in systolic BP over 12-month in the intervention arm compared to the control arm. The secondary outcome is a 12-month difference in non-HDL cholesterol. While each component of our intervention has an evidence base, they have not been tested together in an HIV context. Conclusion: The proposed multicomponent intervention has the potential to improve cardiovascular outcomes in PWH using novel virtual care methods in a patient centered care approach. |
| format | Article |
| id | doaj-art-da6ef2b1777541e78a1c5ce25f8a40cf |
| institution | Kabale University |
| issn | 2578-7470 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | HIV Research & Clinical Practice |
| spelling | doaj-art-da6ef2b1777541e78a1c5ce25f8a40cf2025-01-20T14:37:59ZengTaylor & Francis GroupHIV Research & Clinical Practice2578-74702023-12-0124110.1080/25787489.2023.22617472261747A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trialLewis Musoke0Hayden B. Bosworth1Christina Dickson2Pamela Gentry3Elizabeth Strawbridge4Soumya Subramaniam5Jennifer Gierisch6Valerie Smith7Sandra Woolson8John Pura9Willington Amutuhaire10Susanna Naggie11Julie Schexnayder12Karen Hall13Chris T. Longenecker14Nadine M. Harris15Chantrice Rogers16Puja Van Epps17for V-EXTRA-CVD GroupSection of Infectious Diseases, VA Northeast Ohio Healthcare System, Case Western Reserve UniversityCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemPharmacy Service, VA Maryland Healthcare SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemVA Northeast Ohio Healthcare SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemVA Northeast Ohio Healthcare SystemCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemUniversity of Alabama at Birmingham School of NursingCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care SystemDivision of Cardiology, Department of Global Health, University of WashingtonSection of Infectious Diseases, Atlanta VA Healthcare SystemAtlanta VA Healthcare SystemSection of Infectious Diseases, VA Northeast Ohio Healthcare System, Case Western Reserve UniversityBackground: Veterans living with HIV have up to twice the risk of atherosclerotic cardiovascular disease (ASCVD) compared to those without HIV. Objective: Our study seeks to test a non-physician led virtual self-management implementation strategy to reduce ASCVD risk among people living with HIV (PWH). We aim to conduct a randomized control trial among PWH (n = 300) with a diagnosis of hypertension (HTN) who are enrolled in Veterans Health Administration (VHA) clinics, on suppressive antiretroviral therapy (ART), randomized 1:1 to intervention vs. education control for a 12-month duration. Methods: Using human centered design approach, we have adapted a previous 5-component telehealth focused, non-physician led intervention to a Veteran population. The education control arm receives enhanced education in addition to usual care. The primary outcome is 6 mmHg reduction in systolic BP over 12-month in the intervention arm compared to the control arm. The secondary outcome is a 12-month difference in non-HDL cholesterol. While each component of our intervention has an evidence base, they have not been tested together in an HIV context. Conclusion: The proposed multicomponent intervention has the potential to improve cardiovascular outcomes in PWH using novel virtual care methods in a patient centered care approach.http://dx.doi.org/10.1080/25787489.2023.2261747hivcholesterolhypertensionatherosclerotic cardiovascular disease |
| spellingShingle | Lewis Musoke Hayden B. Bosworth Christina Dickson Pamela Gentry Elizabeth Strawbridge Soumya Subramaniam Jennifer Gierisch Valerie Smith Sandra Woolson John Pura Willington Amutuhaire Susanna Naggie Julie Schexnayder Karen Hall Chris T. Longenecker Nadine M. Harris Chantrice Rogers Puja Van Epps for V-EXTRA-CVD Group A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial HIV Research & Clinical Practice hiv cholesterol hypertension atherosclerotic cardiovascular disease |
| title | A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial |
| title_full | A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial |
| title_fullStr | A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial |
| title_full_unstemmed | A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial |
| title_short | A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial |
| title_sort | telehealth delivered intervention to extend the veteran hiv treatment cascade for cardiovascular disease prevention v extra cvd study protocol for a randomized controlled trial |
| topic | hiv cholesterol hypertension atherosclerotic cardiovascular disease |
| url | http://dx.doi.org/10.1080/25787489.2023.2261747 |
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