β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal

In the last decade, the widespread use of transvaginal ultrasound and the availability of highly specific serum assays of human chorionic gonadotropin (hCG) have become mainstays in the evaluation of early pregnancy. These tests have revolutionized the management of pregnancies of unknown location a...

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Main Authors: Demetrio Larraín, Javier Caradeux
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2024/8351132
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author Demetrio Larraín
Javier Caradeux
author_facet Demetrio Larraín
Javier Caradeux
author_sort Demetrio Larraín
collection DOAJ
description In the last decade, the widespread use of transvaginal ultrasound and the availability of highly specific serum assays of human chorionic gonadotropin (hCG) have become mainstays in the evaluation of early pregnancy. These tests have revolutionized the management of pregnancies of unknown location and markedly reduced the morbidity and mortality associated with the misdiagnosis of ectopic pregnancy. However, despite several advances, their misuse and misinterpretations are still common, leading to an increased use of healthcare resources, patient misinformation, and anxiety. This narrative review aims to succinctly summarize the β-hCG dynamics in early gestation and provide general gynecologists a practical approach to patients with first-trimester symptomatic pregnancy.
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series Obstetrics and Gynecology International
spelling doaj-art-da3138d3e7ef4dfa9c533eb8545137a82025-02-03T06:14:54ZengWileyObstetrics and Gynecology International1687-95972024-01-01202410.1155/2024/8351132β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated ReappraisalDemetrio Larraín0Javier Caradeux1Department of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyIn the last decade, the widespread use of transvaginal ultrasound and the availability of highly specific serum assays of human chorionic gonadotropin (hCG) have become mainstays in the evaluation of early pregnancy. These tests have revolutionized the management of pregnancies of unknown location and markedly reduced the morbidity and mortality associated with the misdiagnosis of ectopic pregnancy. However, despite several advances, their misuse and misinterpretations are still common, leading to an increased use of healthcare resources, patient misinformation, and anxiety. This narrative review aims to succinctly summarize the β-hCG dynamics in early gestation and provide general gynecologists a practical approach to patients with first-trimester symptomatic pregnancy.http://dx.doi.org/10.1155/2024/8351132
spellingShingle Demetrio Larraín
Javier Caradeux
β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal
Obstetrics and Gynecology International
title β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal
title_full β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal
title_fullStr β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal
title_full_unstemmed β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal
title_short β-Human Chorionic Gonadotropin Dynamics in Early Gestational Events: A Practical and Updated Reappraisal
title_sort β human chorionic gonadotropin dynamics in early gestational events a practical and updated reappraisal
url http://dx.doi.org/10.1155/2024/8351132
work_keys_str_mv AT demetriolarrain bhumanchorionicgonadotropindynamicsinearlygestationaleventsapracticalandupdatedreappraisal
AT javiercaradeux bhumanchorionicgonadotropindynamicsinearlygestationaleventsapracticalandupdatedreappraisal