Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis
<b>Background</b> Abdominal ultrasound (US) is a reliable method for visualizing gastric wall layers and measuring their thickness. The objective of this study is to characterize the ultrasound features of <i>H. pylori</i>-induced gastritis and assess its predictive potential...
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MDPI AG
2024-12-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/14/1/12 |
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| author | Fulvia Terracciano Antonella Marra Veronica Nassisi Chiara Lillo Fabrizio Bossa Sonia Carparelli Francesco Cocomazzi Maria Rosa Valvano Giuseppe Losurdo Alfredo Di Leo Francesco Perri |
| author_facet | Fulvia Terracciano Antonella Marra Veronica Nassisi Chiara Lillo Fabrizio Bossa Sonia Carparelli Francesco Cocomazzi Maria Rosa Valvano Giuseppe Losurdo Alfredo Di Leo Francesco Perri |
| author_sort | Fulvia Terracciano |
| collection | DOAJ |
| description | <b>Background</b> Abdominal ultrasound (US) is a reliable method for visualizing gastric wall layers and measuring their thickness. The objective of this study is to characterize the ultrasound features of <i>H. pylori</i>-induced gastritis and assess its predictive potential role for this condition. <b>Methods</b> A cohort of 119 patients underwent gastroscopy with biopsy and abdominal US to evaluate antral wall thickness (AWT), submucosal wall thickness (SLT), mucosal wall thickness (MLT), gastric motility, and the presence of ingested material. They were divided into three groups: group A (normal mucosa without <i>H. pylori</i> infection), group B (gastritis <i>H. pylori</i> negative) and group C (gastritis <i>H. pylori</i> positive). <b>Results</b>: SLT and reduced gastric motility were significantly increased in the <i>H. pylori</i> gastritis group (<i>p</i> < 0.001). Multivariate analysis identified SLT as the only significant independent predictor of <i>H. pylori</i> gastritis (<i>p</i> < 0.001). An SLT threshold of 1.55 mm was determined as optimal for differentiating <i>H. pylori</i>-positive patients from -negative, yielding a sensitivity of 77% and a specificity of 72%. <b>Conclusions</b> These findings suggest that <i>H. pylori</i> gastritis is characterized by submucosal layer thickening and impaired gastric motility. |
| format | Article |
| id | doaj-art-da1c0f8ad3ae4be5b293f2d7086931c9 |
| institution | Kabale University |
| issn | 2079-6382 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj-art-da1c0f8ad3ae4be5b293f2d7086931c92025-01-24T13:18:31ZengMDPI AGAntibiotics2079-63822024-12-011411210.3390/antibiotics14010012Ultrasound Features of <i>Helicobacter pylori</i>-Related GastritisFulvia Terracciano0Antonella Marra1Veronica Nassisi2Chiara Lillo3Fabrizio Bossa4Sonia Carparelli5Francesco Cocomazzi6Maria Rosa Valvano7Giuseppe Losurdo8Alfredo Di Leo9Francesco Perri10Division of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyDivision of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyInternal Medicine Unit, Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, ItalyDivision of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyDivision of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyDivision of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyDivision of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyQuality and Accreditation Unit, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalySection of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, 70124 Bari, ItalySection of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, 70124 Bari, ItalyDivision of Gastroenterology & Endoscopy, IRCCS, Fondazione “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, Italy<b>Background</b> Abdominal ultrasound (US) is a reliable method for visualizing gastric wall layers and measuring their thickness. The objective of this study is to characterize the ultrasound features of <i>H. pylori</i>-induced gastritis and assess its predictive potential role for this condition. <b>Methods</b> A cohort of 119 patients underwent gastroscopy with biopsy and abdominal US to evaluate antral wall thickness (AWT), submucosal wall thickness (SLT), mucosal wall thickness (MLT), gastric motility, and the presence of ingested material. They were divided into three groups: group A (normal mucosa without <i>H. pylori</i> infection), group B (gastritis <i>H. pylori</i> negative) and group C (gastritis <i>H. pylori</i> positive). <b>Results</b>: SLT and reduced gastric motility were significantly increased in the <i>H. pylori</i> gastritis group (<i>p</i> < 0.001). Multivariate analysis identified SLT as the only significant independent predictor of <i>H. pylori</i> gastritis (<i>p</i> < 0.001). An SLT threshold of 1.55 mm was determined as optimal for differentiating <i>H. pylori</i>-positive patients from -negative, yielding a sensitivity of 77% and a specificity of 72%. <b>Conclusions</b> These findings suggest that <i>H. pylori</i> gastritis is characterized by submucosal layer thickening and impaired gastric motility.https://www.mdpi.com/2079-6382/14/1/12<i>H. pylori</i> gastritisabdominal ultrasoundsubmucosal wall thicknessgastric motility |
| spellingShingle | Fulvia Terracciano Antonella Marra Veronica Nassisi Chiara Lillo Fabrizio Bossa Sonia Carparelli Francesco Cocomazzi Maria Rosa Valvano Giuseppe Losurdo Alfredo Di Leo Francesco Perri Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis Antibiotics <i>H. pylori</i> gastritis abdominal ultrasound submucosal wall thickness gastric motility |
| title | Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis |
| title_full | Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis |
| title_fullStr | Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis |
| title_full_unstemmed | Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis |
| title_short | Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis |
| title_sort | ultrasound features of i helicobacter pylori i related gastritis |
| topic | <i>H. pylori</i> gastritis abdominal ultrasound submucosal wall thickness gastric motility |
| url | https://www.mdpi.com/2079-6382/14/1/12 |
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