The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing their formation in Caenorhabditis elegans

Meiotic crossover recombination is essential for both accurate chromosome segregation and the generation of new haplotypes for natural selection to act upon. This requirement is known as crossover assurance and is one example of crossover control. While the conserved role of the ATPase, PCH-2, durin...

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Bibliographic Details
Main Authors: Bhumil Patel, Maryke Grobler, Alberto Herrera, Elias Logari, Valery Ortiz, Needhi Bhalla
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
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Online Access:https://elifesciences.org/articles/102409
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