Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium
Purpose. To evaluate the effectiveness and safety of Ologen implantation versus conjunctival autograft transplantation for primary pterygium. Methods. A retrospective case-series analysis. Thirty-one eyes of 29 patients were included in the Ologen group and 42 eyes of 35 patients in the autograft gr...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2018/1617520 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832568109728268288 |
|---|---|
| author | Xiuping Chen Fei Yuan |
| author_facet | Xiuping Chen Fei Yuan |
| author_sort | Xiuping Chen |
| collection | DOAJ |
| description | Purpose. To evaluate the effectiveness and safety of Ologen implantation versus conjunctival autograft transplantation for primary pterygium. Methods. A retrospective case-series analysis. Thirty-one eyes of 29 patients were included in the Ologen group and 42 eyes of 35 patients in the autograft group. The patients were followed up for 1 year and evaluated for slit-lamp biomicroscopy, intraocular pressure, and adverse events. Recurrence rate, complications, and final appearance of the cases were evaluated prospectively. Result. At 1 year after operation, 2 eyes recurred (6.5%) in the Ologen group and 4 eyes recurred (9.52%) in the autograft group. There was no statistically significant difference between both groups (P=0.157, χ2 = 3.781). There was no occurrence of serious complications. Two eyes among the 31 eyes of the Ologen group were conjunctivitis; the incidence of complications was 6.45% (2 eyes). There was conjunctivitis in 3 eyes of the autograft group, 1 eye complicated with symblepharon, and 1 eye with conjunctival granuloma; the incidence of complications was 11.90% (5 eyes), and there was no statistically significant difference between both groups (P=0.094). The conjuntiva was less vascular and inflamed at 1 month postoperatively in the Ologen group than in the autograft group. Conclusions. Ologen transplantation was technically easier, provided short operative time compared with conjunctival autograft transplantation, and preserved healthy conjunctiva with less complication and less recurrence; it may be a new, safe, and effective alternative for improving the short-term success rate of primary surgery. |
| format | Article |
| id | doaj-art-d9eaf07e7dd14b8ea609933cee3806f2 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-d9eaf07e7dd14b8ea609933cee3806f22025-02-03T00:59:47ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/16175201617520Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of PterygiumXiuping Chen0Fei Yuan1Department of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai, ChinaDepartment of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai, ChinaPurpose. To evaluate the effectiveness and safety of Ologen implantation versus conjunctival autograft transplantation for primary pterygium. Methods. A retrospective case-series analysis. Thirty-one eyes of 29 patients were included in the Ologen group and 42 eyes of 35 patients in the autograft group. The patients were followed up for 1 year and evaluated for slit-lamp biomicroscopy, intraocular pressure, and adverse events. Recurrence rate, complications, and final appearance of the cases were evaluated prospectively. Result. At 1 year after operation, 2 eyes recurred (6.5%) in the Ologen group and 4 eyes recurred (9.52%) in the autograft group. There was no statistically significant difference between both groups (P=0.157, χ2 = 3.781). There was no occurrence of serious complications. Two eyes among the 31 eyes of the Ologen group were conjunctivitis; the incidence of complications was 6.45% (2 eyes). There was conjunctivitis in 3 eyes of the autograft group, 1 eye complicated with symblepharon, and 1 eye with conjunctival granuloma; the incidence of complications was 11.90% (5 eyes), and there was no statistically significant difference between both groups (P=0.094). The conjuntiva was less vascular and inflamed at 1 month postoperatively in the Ologen group than in the autograft group. Conclusions. Ologen transplantation was technically easier, provided short operative time compared with conjunctival autograft transplantation, and preserved healthy conjunctiva with less complication and less recurrence; it may be a new, safe, and effective alternative for improving the short-term success rate of primary surgery.http://dx.doi.org/10.1155/2018/1617520 |
| spellingShingle | Xiuping Chen Fei Yuan Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium Journal of Ophthalmology |
| title | Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium |
| title_full | Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium |
| title_fullStr | Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium |
| title_full_unstemmed | Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium |
| title_short | Ologen Implantation versus Conjunctival Autograft Transplantation for Treatment of Pterygium |
| title_sort | ologen implantation versus conjunctival autograft transplantation for treatment of pterygium |
| url | http://dx.doi.org/10.1155/2018/1617520 |
| work_keys_str_mv | AT xiupingchen ologenimplantationversusconjunctivalautografttransplantationfortreatmentofpterygium AT feiyuan ologenimplantationversusconjunctivalautografttransplantationfortreatmentofpterygium |