Correlating disordered activation domain ensembles with gene expression levels

Transcription factor proteins bind to specific DNA promoter sequences and initiate gene transcription. These proteins often contain intrinsically disordered activation domains (ADs) that regulate their transcriptional activity. Like other disordered protein regions, ADs do not have a fixed three-dim...

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Bibliographic Details
Main Authors: Eduardo Flores, Aleah R. Camacho, Estefania Cuevas-Zepeda, Mary B. McCoy, Feng Yu, Max V. Staller, Shahar Sukenik
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Biophysical Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2667074724000545
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