Selective Evolution of Ligands by Exponential Enrichment to Identify RNA Aptamers against Shiga Toxins

Infection with Shiga toxin- (Stx-) producing E. coli causes life threatening hemolytic uremic syndrome (HUS), a leading cause of acute renal failure in children. Of the two antigenically distinct toxins, Stx1 and Stx2, Stx2 is more firmly linked with the development of HUS. In the present study, sel...

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Bibliographic Details
Main Authors: Sreerupa Challa, Saul Tzipori, Abhineet Sheoran
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2014/214929
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