Oxidant-free cross-dehydrogenative oxyalkylation enables late-stage functionalization of drugs
Late-stage functionalization is an attractive strategy that allows chemists to bypass lengthy synthetic processes, facilitating the rapid generation of drug analogs with potentially enhanced pharmacokinetic and pharmacological properties. This study describes a novel approach for cross-dehydrogenati...
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| Main Authors: | Weiqiu Liang, Jiahao Li, Jianbin Li, Chengda Wu, Zhiyu Tu, Bo-Shuai Mu, Yang Xu, Longlong Song, Mengxin Xu, Xi-Yang Cui, Chao-Jun Li, Zhibo Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-04-01
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| Series: | The Innovation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666675825000128 |
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