Global stability of a network-based SIS epidemic model with a general nonlinear incidence rate

In this paper, we develop and analyze an SIS epidemic model with a general nonlinear incidence rate, as well as degree-dependent birth and natural death, on heterogeneous networks. We analytically derive the epidemic threshold $R_0$ which completely governs the disease dynamics: when $R_0<1 the=&...

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Bibliographic Details
Main Authors: Shouying Huang, Jifa Jiang
Format: Article
Language:English
Published: AIMS Press 2016-04-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2016016
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Summary:In this paper, we develop and analyze an SIS epidemic model with a general nonlinear incidence rate, as well as degree-dependent birth and natural death, on heterogeneous networks. We analytically derive the epidemic threshold $R_0$ which completely governs the disease dynamics: when $R_0<1 the="" disease-free="" equilibrium="" is="" globally="" asymptotically="" stable="" i="" e="" the="" disease="" will="" die="" out="" when="" r_0="">1$, the disease is permanent. It is interesting that the threshold value $R_0$ bears no relation to the functional form of the nonlinear incidence rate and degree-dependent birth. Furthermore, by applying an iteration scheme and the theory of cooperative system respectively, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. Our results improve and generalize some known results. To illustrate the theoretical results, the corresponding numerical simulations are also given.
ISSN:1551-0018