Association between red blood cell distribution width and genetic risk in patients with rheumatoid arthritis: a prospective cohort study and Mendelian randomization analysis

Association between red blood cell distribution width and genetic risk in patients with rheumatoid arthritis: a prospective cohort study and Mendelian randomization analysis

Abstract Objective Elevated red blood cell distribution width (RDW) is associated with increased risk of rheumatoid arthritis (RA), but the potential interactions of RDW with genetic risk of incident RA remain unclear. This study aimed to investigate the associations between RDW, genetics, and the r...

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Bibliographic Details
Main Authors: Mingyang Chen, Jing Lei, Zhenqiu Liu, Renjia Zhao, Yanfeng Jiang, Kelin Xu, Tiejun Zhang, Chen Suo, Xingdong Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Rheumatology
Subjects:
Rheumatoid arthritis
Red blood cell distribution width
Genetic risk
Mendelian randomization
Colocalization
Online Access:https://doi.org/10.1186/s41927-024-00451-1
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https://doi.org/10.1186/s41927-024-00451-1

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