Role of Ischemia/Reperfusion and Oxidative Stress in Shock State

Role of Ischemia/Reperfusion and Oxidative Stress in Shock State

Shock is a life-threatening condition characterized by inadequate tissue perfusion leading to systemic hypoxia and metabolic failure. Ischemia/reperfusion (I/R) injury exacerbates shock progression through oxidative stress and immune dysregulation, contributing to multi-organ dysfunction. This narra...

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Bibliographic Details
Main Authors: Yarielis Ivette Vázquez-Galán, Sandra Guzmán-Silahua, Walter Ángel Trujillo-Rangel, Simón Quetzalcoatl Rodríguez-Lara
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
shock
ischemia/reperfusion injury
oxidative stress
immune dysregulation
HIF pathway
inflammatory response
Online Access:https://www.mdpi.com/2073-4409/14/11/808
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