INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS

Background: gram-negative bacteria-salmonella typhi and gram-positive bacteria-staphylococcus aureus are types of bacteria that cause infectious disease among several areas in Indonesia. Staphylococcus aureus often found in skin lesions injury. Red ginger extract (Zingiber officinale var rubrum) has...

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Main Authors: Firnanda Iptita Dewi, Manik retno Wahyunitisari
Format: Article
Language:English
Published: Universitas Airlangga 2018-09-01
Series:Journal of Vocational Health Studies
Subjects:
Online Access:https://e-journal.unair.ac.id/JVHS/article/view/9692
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author Firnanda Iptita Dewi
Manik retno Wahyunitisari
author_facet Firnanda Iptita Dewi
Manik retno Wahyunitisari
author_sort Firnanda Iptita Dewi
collection DOAJ
description Background: gram-negative bacteria-salmonella typhi and gram-positive bacteria-staphylococcus aureus are types of bacteria that cause infectious disease among several areas in Indonesia. Staphylococcus aureus often found in skin lesions injury. Red ginger extract (Zingiber officinale var rubrum) has been known for its medicinal value especially as an antibacterial agent. Purpose: This study aims to test the ability of Zingiber officinale var rubrum on inhibiting the growth of Staphylococcus aureus. Methods: the activity of the antibacterial agent was calculated based on Minimum Inhibitory Concentration (MIC) using dilution method. Minimum Inhibitory Concentration of extract was determined by incubating bacteria with the extract overnight at 37 0C. Changes in turbidity and inhibition on bacterial growth were then observed. Result: The results show that minimum concentration for inhibitory effect was 1000 μg/mL.Conclusion: extract of Zingiber officinale var rubrum have an inhibitory effect on the growth of Staphylococcus aureus but no activity of killing bacterial was observed on the concentration given.
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spelling doaj-art-d980ebd318ed4b458dde70c3253e789f2025-02-03T00:58:52ZengUniversitas AirlanggaJournal of Vocational Health Studies2580-71612580-717X2018-09-011311311610.20473/jvhs.V1.I3.2018.113-1164926INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUSFirnanda Iptita Dewi0Manik retno Wahyunitisari1Student of Medical Analyst, Department of Health, Faculty of Vocational Education, Universitas Airlangga, Surabaya-IndonesiaDepartment of Microbiology, Faculty of Medicine, Universitas Airlangga, Surabaya-IndonesiaBackground: gram-negative bacteria-salmonella typhi and gram-positive bacteria-staphylococcus aureus are types of bacteria that cause infectious disease among several areas in Indonesia. Staphylococcus aureus often found in skin lesions injury. Red ginger extract (Zingiber officinale var rubrum) has been known for its medicinal value especially as an antibacterial agent. Purpose: This study aims to test the ability of Zingiber officinale var rubrum on inhibiting the growth of Staphylococcus aureus. Methods: the activity of the antibacterial agent was calculated based on Minimum Inhibitory Concentration (MIC) using dilution method. Minimum Inhibitory Concentration of extract was determined by incubating bacteria with the extract overnight at 37 0C. Changes in turbidity and inhibition on bacterial growth were then observed. Result: The results show that minimum concentration for inhibitory effect was 1000 μg/mL.Conclusion: extract of Zingiber officinale var rubrum have an inhibitory effect on the growth of Staphylococcus aureus but no activity of killing bacterial was observed on the concentration given.https://e-journal.unair.ac.id/JVHS/article/view/9692zingiber officinale var rubrumextractinhibitorystaphylococcus aureus
spellingShingle Firnanda Iptita Dewi
Manik retno Wahyunitisari
INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS
Journal of Vocational Health Studies
zingiber officinale var rubrum
extract
inhibitory
staphylococcus aureus
title INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS
title_full INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS
title_fullStr INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS
title_full_unstemmed INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS
title_short INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS
title_sort inhibitory activity of zingiber officinale var rubrum extract against staphylococcus aureus
topic zingiber officinale var rubrum
extract
inhibitory
staphylococcus aureus
url https://e-journal.unair.ac.id/JVHS/article/view/9692
work_keys_str_mv AT firnandaiptitadewi inhibitoryactivityofzingiberofficinalevarrubrumextractagainststaphylococcusaureus
AT manikretnowahyunitisari inhibitoryactivityofzingiberofficinalevarrubrumextractagainststaphylococcusaureus