Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man

Thyrotoxic induced hypokalemic periodic paralysis is a rare disorder that had been described in middle-aged men, predominantly Asians and Hispanics. This case presented with generalized weakness and hypokalemia after changing prescription for levothyroxine and starting prednisone to treat upper resp...

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Main Authors: Andrew Word, Kevin Davidson, Essam Elsayed
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/616930
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author Andrew Word
Kevin Davidson
Essam Elsayed
author_facet Andrew Word
Kevin Davidson
Essam Elsayed
author_sort Andrew Word
collection DOAJ
description Thyrotoxic induced hypokalemic periodic paralysis is a rare disorder that had been described in middle-aged men, predominantly Asians and Hispanics. This case presented with generalized weakness and hypokalemia after changing prescription for levothyroxine and starting prednisone to treat upper respiratory infection in a previously asymptomatic middle-aged Hispanic male. In this paper, we will go over the clinical presentation, mechanisms, and treatment of thyrotoxic induced hypokalemic periodic paralysis. Our objectives are to identify the classic constellation of findings in thyrotoxic periodic paralysis and to recognize the importance of considering thyrotoxic periodic paralysis among patients with hypokalemia.
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spelling doaj-art-d97b72a68b9e4f9baef9dcbdf54ce3452025-02-03T06:11:02ZengWileyCase Reports in Endocrinology2090-65012090-651X2012-01-01201210.1155/2012/616930616930Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged ManAndrew Word0Kevin Davidson1Essam Elsayed2Departement of Internal Medicine, UT Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390, USADepartement of Internal Medicine, UT Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390, USADepartement of Internal Medicine, UT Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390, USAThyrotoxic induced hypokalemic periodic paralysis is a rare disorder that had been described in middle-aged men, predominantly Asians and Hispanics. This case presented with generalized weakness and hypokalemia after changing prescription for levothyroxine and starting prednisone to treat upper respiratory infection in a previously asymptomatic middle-aged Hispanic male. In this paper, we will go over the clinical presentation, mechanisms, and treatment of thyrotoxic induced hypokalemic periodic paralysis. Our objectives are to identify the classic constellation of findings in thyrotoxic periodic paralysis and to recognize the importance of considering thyrotoxic periodic paralysis among patients with hypokalemia.http://dx.doi.org/10.1155/2012/616930
spellingShingle Andrew Word
Kevin Davidson
Essam Elsayed
Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
Case Reports in Endocrinology
title Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
title_full Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
title_fullStr Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
title_full_unstemmed Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
title_short Levothyroxine and Prednisone Causing Generalized Weakness in a Middle-Aged Man
title_sort levothyroxine and prednisone causing generalized weakness in a middle aged man
url http://dx.doi.org/10.1155/2012/616930
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