An integrated investigation of mitochondrial genes in COPD reveals the causal effect of NDUFS2 by regulating pulmonary macrophages

Abstract Background Despite the increasing body of evidence that mitochondrial activities implicate in chronic obstructive pulmonary disease (COPD), we are still far from a causal-logical and mechanistic understanding of the mitochondrial malfunctions in COPD pathogenesis. Results Differential expre...

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Bibliographic Details
Main Authors: Xiaoli Zou, Qiqing Huang, Tutu Kang, Shaoran Shen, Chenxi Cao, Jianqing Wu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Biology Direct
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Online Access:https://doi.org/10.1186/s13062-025-00593-3
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