Contribution of genetics to hematopoietic stem cell mobilization: a genome-wide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor

Contribution of genetics to hematopoietic stem cell mobilization: a genome-wide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor

Hematopoietic stem and progenitor cells (HSPC) from mobilized blood are the preferred graft source for allogeneic and autologous stem cell transplantation. The efficiency of CD34+ cell mobilization with granulocyte colony-stimulating factor (G-CSF) varies significantly between individuals, but is r...

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Main Authors: Miriam Stenzinger, Susanne Beck, Iordanis Ourailidis, Anna-Lena Volckmar, Nagarajan Paramasivam, Aysel Ahadova, Aitzkoa Lopez de Lapuente Portilla, Phuong La Yen, Bjorn Nilsson, Justo Lorenzo Bermejo, Halvard Bonig, Jan Budczies
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-06-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12096
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https://haematologica.org/article/view/12096

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