Pathophysiological mechanisms underlying early brain injury and delayed cerebral ischemia in the aftermath of aneurysmal subarachnoid hemorrhage: a comprehensive analysis

Pathophysiological mechanisms underlying early brain injury and delayed cerebral ischemia in the aftermath of aneurysmal subarachnoid hemorrhage: a comprehensive analysis

Early brain injury (EBI) and delayed cerebral ischemia (DCI) are pivotal contributors to morbidity and mortality following aneurysmal subarachnoid hemorrhage (aSAH). Despite advances that have reduced mortality and incidence, aSAH remains a significant public health concern due to its early onset, l...

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Bibliographic Details
Main Authors: Hendrik Stragier, Hans Vandersmissen, Sofie Ordies, Steven Thiessen, Dieter Mesotten, Dieter Peuskens, Hugo Ten Cate
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neurology
Subjects:
aneurysmal subarachnoid hemorrhage
delayed cerebral ischemia
early brain injury
thrombo-inflammation
neuro-inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1587091/full
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