Interactions of Self-Assembled <i>Bletilla Striata</i> Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles

Interactions of Self-Assembled <i>Bletilla Striata</i> Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles

Amphiphilic copolymers of stearic acid (SA)-modified <i>Bletilla striata</i> polysaccharides (BSPs-SA) with three different degrees of substitution (DSs) were synthesized. The effects of DS values on the properties of BSPs-SA nanoparticles were evaluated. Drug state, cytotoxicity, and hi...

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Bibliographic Details
Main Authors: Guangyuan Zhang, Jin Qiao, Xin Liu, Yuran Liu, Ji Wu, Long Huang, Danyang Ji, Qingxiang Guan
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceutics
Subjects:
<i>Bletilla striata</i> polysaccharide
nanoparticle
interaction
bioavailability
tissue distribution
Online Access:https://www.mdpi.com/1999-4923/11/1/43
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