Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome‐Wide Association and Mendelian Randomization Study

Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome‐Wide Association and Mendelian Randomization Study

Background Observational studies have reported associations between primary aldosteronism (PA) and cardiovascular outcomes, including coronary artery diseases (CAD), congestive heart failure (CHF), and stroke. However, establishing causality remains a challenge due to the lack of randomized controll...

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Main Authors: Kosuke Inoue, Tatsuhiko Naito, Ryosuke Fuji, Kyuto Sonehara, Kenichi Yamamoto, Ryuta Baba, Takaya Kodama, Yu Otagaki, Akira Okada, Kiyotaka Itcho, Kazuhiro Kobuke, Haruya Ohno, Takayuki Morisaki, Noboru Hattori, Atsushi Goto, Tetsuo Nishikawa, Kenji Oki, Yukinori Okada
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiovascular disease
cross‐ancestry meta‐analysis
genome‐wide association studies
Mendelian randomization
primary aldosteronism
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.034180
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https://www.ahajournals.org/doi/10.1161/JAHA.123.034180

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