Bone marrow mesenchymal stem cells overexpressing stromal cell- derived factor 1 aid in bone formation in osteoporotic mice

Bone marrow mesenchymal stem cells overexpressing stromal cell- derived factor 1 aid in bone formation in osteoporotic mice

Abstract Background Osteoporosis is characterized by low systemic bone mineral content and destruction of bone microarchitecture. Promoting bone regeneration and reversing its loss by infusion of exogenous bone marrow mesenchymal stem cells (BMSCs) is a potentially effective treatment for osteoporos...

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Bibliographic Details
Main Authors: Yanghao Wang, Ya Xiao, XinYu Yang, Fei He, Jun Hu, Guang Yang, Weizhou Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Bone marrow mesenchymal stem cells
Stromal cell-derived factor 1
Osteoporosis
Bone density
Wnt signaling
Online Access:https://doi.org/10.1186/s12891-024-07957-2
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