Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism
PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor of the nuclear receptor superfamily that controls the expression of a variety of genes involved in fatty acid metabolism, adipogenesis, and insulin sensitivity. While endogenous ligands of PPARγ include f...
Saved in:
Main Authors: | Alice J. Kroker, John B. Bruning |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
|
Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2015/816856 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury
by: Guanting Li, et al.
Published: (2025-01-01) -
Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
by: Ajit A. Kulkarni, et al.
Published: (2012-01-01) -
Solution Structures of PPARγ2/RXRα Complexes
by: Judit Osz, et al.
Published: (2012-01-01) -
PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
by: Robert I. Glazer, et al.
Published: (2008-01-01) -
Structural Features and Transcriptional Activity of Chicken PPARs (α, β, and γ)
by: Ichiro Takada, et al.
Published: (2013-01-01)