Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism

PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor of the nuclear receptor superfamily that controls the expression of a variety of genes involved in fatty acid metabolism, adipogenesis, and insulin sensitivity. While endogenous ligands of PPARγ include f...

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Bibliographic Details
Main Authors: Alice J. Kroker, John B. Bruning
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2015/816856
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