RORγt is crucial for gut homeostasis by regulating the expression of HB-EGF rather than IL-22 in activated ILC3s

Summary: RORγt inhibition shows potential for treating T helper 17 (Th17) cell-related inflammatory disorders. However, there is a lack of a comprehensive understanding of its influence on the immune system. RORγt also serves as the master regulator of type 3 innate lymphoid cells (ILC3s). Although...

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Bibliographic Details
Main Authors: Peng Li, Yime Zhang, Yang Shen, Xingyu Zhao, Rong Mu, Chao Zhong
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725005649
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