Exosome mediated delivery of Epigallocatechin 3 gallate as a novel approach to alleviate psoriasis symptoms through cytokine and apoptotic pathway modulation

Exosome mediated delivery of Epigallocatechin 3 gallate as a novel approach to alleviate psoriasis symptoms through cytokine and apoptotic pathway modulation

Abstract Psoriasis is a chronic skin disorder with significant individual and societal impacts. Current therapies often lack efficacy, are costly, or cause side effects, necessitating new treatments. This study explores regenerative therapies—exosomes, mesenchymal stem cells (MSCs), epigallocatechin...

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Bibliographic Details
Main Authors: Mohamed S. Kishta, Ahmed A. Abd-Rabou, Garo K. Sarkissian, Ahmed I. Elwakil, Dana M. Elsabry, Youssef M. Zagzoug, Sohaila R. Hussein, Ahmed N. Abdallah
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Psoriasis
Bone marrow mesenchymal stem cells
Stem cell-derived exosomes
Epigallocatechin-3-gallate nanoparticles
Epigallocatechin-3-gallate-loaded exosomes
Online Access:https://doi.org/10.1038/s41598-025-10886-2
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https://doi.org/10.1038/s41598-025-10886-2

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