Multi-omics whole-genome characterization of the copy number landscape of metastatic pancreatic ductal adenocarcinoma

Multi-omics whole-genome characterization of the copy number landscape of metastatic pancreatic ductal adenocarcinoma

Summary: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with limited therapeutic options. While genome profiling has benefitted clinical decision-making in many cancer types, PDAC remains among the most lethal solid cancers and has relatively few clinically actionable molecul...

Full description

Saved in:
Bibliographic Details
Main Authors: James T. Topham, Joanna M. Karasinska, Andrew Metcalfe, Hassan A. Ali, Steve E. Kalloger, Maya Kevorkova, Emma Titmuss, Gian Luca Negri, Sandra E. Spencer, Gun Ho Jang, Grainne M. O’Kane, Richard A. Moore, Andrew J. Mungall, Jonathan M. Loree, Faiyaz Notta, Julie M. Wilson, Oliver F. Bathe, Patricia A. Tang, Rachel Goodwin, Gregg B. Morin, Jennifer J. Knox, Steven Gallinger, Janessa Laskin, Marco A. Marra, Steven J.M. Jones, Daniel J. Renouf, David F. Schaeffer
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Cancer
Genomics
Proteomics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225014373
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2589004225014373

Similar Items