Restoration of Sestrin 3 Expression Mitigates Cardiac Oxidative Damage in Ischemia–Reperfusion Injury Model

Restoration of Sestrin 3 Expression Mitigates Cardiac Oxidative Damage in Ischemia–Reperfusion Injury Model

Cardiac ischemia–reperfusion injury (IRI) occurs when blood flow is restored to the myocardium after a period of ischemia, leading to oxidative stress and subsequent myocardial cell damage, primarily due to the accumulation of reactive oxygen species (ROS). In our previous research, we identified th...

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Bibliographic Details
Main Authors: Mina Park, Sunghye Cho, Dongtak Jeong
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antioxidants
Subjects:
ischemia–reperfusion injury
sestrin
miR-25
ROS
oxidative damage
apoptosis
Online Access:https://www.mdpi.com/2076-3921/14/1/61
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