A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals
This study addresses sensitivity performance, a pivotal parameter of Positron Emission Tomography (PET) imaging, which measures the system’s ability to detect and precisely measure radiotracer signals. It primarily depends on the scintillation material and the system’s axial field of view (AFOV). En...
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| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/01/e3sconf_icegc2024_00089.pdf |
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| author | El Ouaridi Abdallah Ait Elcadi Zakaria Mkimel Mounir Bougteb Mustapha El Baydaoui Redouane |
| author_facet | El Ouaridi Abdallah Ait Elcadi Zakaria Mkimel Mounir Bougteb Mustapha El Baydaoui Redouane |
| author_sort | El Ouaridi Abdallah |
| collection | DOAJ |
| description | This study addresses sensitivity performance, a pivotal parameter of Positron Emission Tomography (PET) imaging, which measures the system’s ability to detect and precisely measure radiotracer signals. It primarily depends on the scintillation material and the system’s axial field of view (AFOV). Enhancing this performance can significantly increase overall system performance and clinical practice. This research evaluates the sensitivity of a simulated PET model based on different scintillation materials and extended AFOV values, following the NEMA NU 2-2018 protocol. A standard PET system model with an AFOV of 15.9 cm was developed using the GATE Monte Carlo simulation toolkit (v9.2), along with detailed modelling of the NEMA NU 2-2018 sensitivity phantom. Simulations examined six scintillation materials (BGO, GSO, LSO, LYSO, LuAP, and NaI) across AFOV sizes from 15.9 cm to 79.5 cm. Results showed a substantial increase in sensitivity with AFOV extension, following a quadratic relationship. BGO, LuAP, and LSO crystals demonstrated notable performance enhancements, while LYSO showed acceptable results. This study underscores the potential of AFOV extension and high-performance scintillation crystals to enhance sensitivity in PET scanners, thereby improving imaging quality and potentially advancing clinical practice. |
| format | Article |
| id | doaj-art-d79140f56c6a4432b80c221ce805a43e |
| institution | Kabale University |
| issn | 2267-1242 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj-art-d79140f56c6a4432b80c221ce805a43e2025-02-05T10:46:25ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016010008910.1051/e3sconf/202560100089e3sconf_icegc2024_00089A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystalsEl Ouaridi Abdallah0Ait Elcadi Zakaria1Mkimel Mounir2Bougteb Mustapha3El Baydaoui Redouane4Hassan First University of Settat, High Institute of Health Sciences, Laboratory of Health Sciences and TechnologiesElectrical and Computer Engineering, Texas A&M University at QatarHassan First University of Settat, High Institute of Health Sciences, Laboratory of Health Sciences and TechnologiesHassan First University of Settat, High Institute of Health Sciences, Laboratory of Health Sciences and TechnologiesHassan First University of Settat, High Institute of Health Sciences, Laboratory of Health Sciences and TechnologiesThis study addresses sensitivity performance, a pivotal parameter of Positron Emission Tomography (PET) imaging, which measures the system’s ability to detect and precisely measure radiotracer signals. It primarily depends on the scintillation material and the system’s axial field of view (AFOV). Enhancing this performance can significantly increase overall system performance and clinical practice. This research evaluates the sensitivity of a simulated PET model based on different scintillation materials and extended AFOV values, following the NEMA NU 2-2018 protocol. A standard PET system model with an AFOV of 15.9 cm was developed using the GATE Monte Carlo simulation toolkit (v9.2), along with detailed modelling of the NEMA NU 2-2018 sensitivity phantom. Simulations examined six scintillation materials (BGO, GSO, LSO, LYSO, LuAP, and NaI) across AFOV sizes from 15.9 cm to 79.5 cm. Results showed a substantial increase in sensitivity with AFOV extension, following a quadratic relationship. BGO, LuAP, and LSO crystals demonstrated notable performance enhancements, while LYSO showed acceptable results. This study underscores the potential of AFOV extension and high-performance scintillation crystals to enhance sensitivity in PET scanners, thereby improving imaging quality and potentially advancing clinical practice.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/01/e3sconf_icegc2024_00089.pdf |
| spellingShingle | El Ouaridi Abdallah Ait Elcadi Zakaria Mkimel Mounir Bougteb Mustapha El Baydaoui Redouane A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals E3S Web of Conferences |
| title | A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals |
| title_full | A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals |
| title_fullStr | A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals |
| title_full_unstemmed | A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals |
| title_short | A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals |
| title_sort | monte carlo simulation study of the impact of increasing the axial field of view on pet scanner sensitivity with various scintillating crystals |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/01/e3sconf_icegc2024_00089.pdf |
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