Enhanced osteogenic capacity of octacalcium phosphate involving adsorption of stromal-derived factor-1 in a standardized defect of a rat femur

Abstract This study investigated whether octacalcium phosphate (OCP) enhances bone regeneration through its synergistic effect with stromal-derived factor-1 (SDF-1). Recombinant SDF-1 (0.5–5.0 μg) was combined with OCP granules through lyophilization. OCP/SDF-1 granules were implanted into a rat fem...

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Bibliographic Details
Main Authors: Ryuichi Kanabuchi, Ryo Hamai, Yu Mori, Soshi Hamada, Yukari Shiwaku, Yuko Sai, Kaori Tsuchiya, Toshimi Aizawa, Osamu Suzuki
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Journal of Materials Science: Materials in Medicine
Online Access:https://doi.org/10.1007/s10856-025-06872-9
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