Neuroprotective Effects of Stem Cells in Ischemic Stroke
Ischemic stroke, the most common subtype of stroke, has been one of the leading causes of mobility and mortality worldwide. However, it is still lacking of efficient agents. Stem cell therapy, with its vigorous advantages, has attracted researchers around the world. Numerous experimental researches...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2017/4653936 |
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| _version_ | 1832556984790941696 |
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| author | Weilin Xu Jingwei Zheng Liansheng Gao Tao Li Jianmin Zhang Anwen Shao |
| author_facet | Weilin Xu Jingwei Zheng Liansheng Gao Tao Li Jianmin Zhang Anwen Shao |
| author_sort | Weilin Xu |
| collection | DOAJ |
| description | Ischemic stroke, the most common subtype of stroke, has been one of the leading causes of mobility and mortality worldwide. However, it is still lacking of efficient agents. Stem cell therapy, with its vigorous advantages, has attracted researchers around the world. Numerous experimental researches in animal models of stroke have demonstrated the promising efficacy in treating ischemic stroke. The underlying mechanism involved antiapoptosis, anti-inflammation, promotion of angiogenesis and neurogenesis, formation of new neural cells and neuronal circuitry, antioxidation, and blood-brain barrier (BBB) protection. This review would focus on the types and neuroprotective actions of stem cells and its potential mechanisms for ischemic stroke. |
| format | Article |
| id | doaj-art-d71d645d2b5045ffab4e4b56c9a30613 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-d71d645d2b5045ffab4e4b56c9a306132025-02-03T05:44:00ZengWileyStem Cells International1687-966X1687-96782017-01-01201710.1155/2017/46539364653936Neuroprotective Effects of Stem Cells in Ischemic StrokeWeilin Xu0Jingwei Zheng1Liansheng Gao2Tao Li3Jianmin Zhang4Anwen Shao5Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaIschemic stroke, the most common subtype of stroke, has been one of the leading causes of mobility and mortality worldwide. However, it is still lacking of efficient agents. Stem cell therapy, with its vigorous advantages, has attracted researchers around the world. Numerous experimental researches in animal models of stroke have demonstrated the promising efficacy in treating ischemic stroke. The underlying mechanism involved antiapoptosis, anti-inflammation, promotion of angiogenesis and neurogenesis, formation of new neural cells and neuronal circuitry, antioxidation, and blood-brain barrier (BBB) protection. This review would focus on the types and neuroprotective actions of stem cells and its potential mechanisms for ischemic stroke.http://dx.doi.org/10.1155/2017/4653936 |
| spellingShingle | Weilin Xu Jingwei Zheng Liansheng Gao Tao Li Jianmin Zhang Anwen Shao Neuroprotective Effects of Stem Cells in Ischemic Stroke Stem Cells International |
| title | Neuroprotective Effects of Stem Cells in Ischemic Stroke |
| title_full | Neuroprotective Effects of Stem Cells in Ischemic Stroke |
| title_fullStr | Neuroprotective Effects of Stem Cells in Ischemic Stroke |
| title_full_unstemmed | Neuroprotective Effects of Stem Cells in Ischemic Stroke |
| title_short | Neuroprotective Effects of Stem Cells in Ischemic Stroke |
| title_sort | neuroprotective effects of stem cells in ischemic stroke |
| url | http://dx.doi.org/10.1155/2017/4653936 |
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