Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data

Kimchi is a traditional Korean food prepared by fermenting vegetables, such as Chinese cabbage and radishes, which are seasoned with various ingredients, including red pepper powder, garlic, ginger, green onion, fermented seafood (Jeotgal), and salt. The various unique microorganisms and bioactive c...

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Main Authors: Ga Hee Shin, Byeong-Chul Kang, Dai Ja Jang
Format: Article
Language:English
Published: BioMed Central 2016-12-01
Series:Genomics & Informatics
Subjects:
Online Access:http://genominfo.org/upload/pdf/gni-14-222.pdf
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author Ga Hee Shin
Byeong-Chul Kang
Dai Ja Jang
author_facet Ga Hee Shin
Byeong-Chul Kang
Dai Ja Jang
author_sort Ga Hee Shin
collection DOAJ
description Kimchi is a traditional Korean food prepared by fermenting vegetables, such as Chinese cabbage and radishes, which are seasoned with various ingredients, including red pepper powder, garlic, ginger, green onion, fermented seafood (Jeotgal), and salt. The various unique microorganisms and bioactive components in kimchi show antioxidant activity and have been associated with an enhanced immune response, as well as anti-cancer and anti-diabetic effects. Red pepper inhibits decay due to microorganisms and prevents food from spoiling. The vast amount of biological information generated by academic and industrial research groups is reflected in a rapidly growing body of scientific literature and expanding data resources. However, the genome, biological pathway, and related disease data are insufficient to explain the health benefits of kimchi because of the varied and heterogeneous data types. Therefore, we have constructed an appropriate semantic data model based on an integrated food knowledge database and analyzed the functional and biological processes associated with kimchi in silico. This complex semantic network of several entities and connections was generalized to answer complex questions, and we demonstrated how specific disease pathways are related to kimchi consumption.
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institution Kabale University
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publishDate 2016-12-01
publisher BioMed Central
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spelling doaj-art-d6c42ed1ce0c42d8aeeb4a8ed4da40582025-02-02T12:58:29ZengBioMed CentralGenomics & Informatics1598-866X2234-07422016-12-0114422222910.5808/GI.2016.14.4.222179Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published DataGa Hee Shin0Byeong-Chul Kang1Dai Ja Jang2Data Science Center, Insilicogen, Inc., Yongin 16954, Korea.Data Science Center, Insilicogen, Inc., Yongin 16954, Korea.Processing Technology Research Group, Korea Food Research Institute, Seongnam 13539, Korea.Kimchi is a traditional Korean food prepared by fermenting vegetables, such as Chinese cabbage and radishes, which are seasoned with various ingredients, including red pepper powder, garlic, ginger, green onion, fermented seafood (Jeotgal), and salt. The various unique microorganisms and bioactive components in kimchi show antioxidant activity and have been associated with an enhanced immune response, as well as anti-cancer and anti-diabetic effects. Red pepper inhibits decay due to microorganisms and prevents food from spoiling. The vast amount of biological information generated by academic and industrial research groups is reflected in a rapidly growing body of scientific literature and expanding data resources. However, the genome, biological pathway, and related disease data are insufficient to explain the health benefits of kimchi because of the varied and heterogeneous data types. Therefore, we have constructed an appropriate semantic data model based on an integrated food knowledge database and analyzed the functional and biological processes associated with kimchi in silico. This complex semantic network of several entities and connections was generalized to answer complex questions, and we demonstrated how specific disease pathways are related to kimchi consumption.http://genominfo.org/upload/pdf/gni-14-222.pdfcomputer simulationmetabolismsemantic modelingtraditional Korean food
spellingShingle Ga Hee Shin
Byeong-Chul Kang
Dai Ja Jang
Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data
Genomics & Informatics
computer simulation
metabolism
semantic modeling
traditional Korean food
title Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data
title_full Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data
title_fullStr Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data
title_full_unstemmed Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data
title_short Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data
title_sort metabolic pathways associated with kimchi a traditional korean food based on modeling of published data
topic computer simulation
metabolism
semantic modeling
traditional Korean food
url http://genominfo.org/upload/pdf/gni-14-222.pdf
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AT byeongchulkang metabolicpathwaysassociatedwithkimchiatraditionalkoreanfoodbasedonmodelingofpublisheddata
AT daijajang metabolicpathwaysassociatedwithkimchiatraditionalkoreanfoodbasedonmodelingofpublisheddata