An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation

An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation

Abstract This study examines how heart rate (HR) affects hemodynamics in a South African infant with Coarctation of the Aorta. Computed tomography angiography segments aortic coarctation anatomy; Doppler echocardiography derives inlet flow waveforms. Simulations occur at 100, 120, and 160 beats per...

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Bibliographic Details
Main Authors: Jie Wang, Emily Manchester, Alex Skillen, Malebogo Ngoepe, Bernard Keavney, Alistair Revell
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Coarctation of aorta (CoA)
Hemodynamics
Computational fluid dynamics (CFD)
Turbulent wall shear stress
Heart rate
Large Eddy simulation (LES)
Online Access:https://doi.org/10.1038/s41598-025-85522-0
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