Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for thyroid cancer

Abstract Background Thyroid cancer (THCA) exhibits high molecular heterogeneity, posing challenges for precise prognosis and personalized therapy. Most existing models rely on single-omics data and limited algorithms, reducing robustness and clinical value. Methods We integrated five omics layers fr...

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Bibliographic Details
Main Authors: Peng Zhang, Meizhong Qin, Fen Li, Kunpeng Hu, He Huang, Cuicui Li
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02918-0
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