A dynamic peripheral immune landscape during human pregnancy

A dynamic peripheral immune landscape during human pregnancy

Extensive immune adaptations occur during pregnancy to ensure successful delivery. However, these changes can increase the risk of disease in the mother. Here, we conducted single-cell RNA sequencing on peripheral blood mononuclear cells from pregnant women at different stages of pregnancy to elucid...

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Bibliographic Details
Main Authors: Xiuxing Liu, Lei Zhu, Zhaohao Huang, Zhaohuai Li, Runping Duan, He Li, Lihui Xie, Xiaozhen Chen, Wen Ding, Binyao Chen, Yuehan Gao, Juan Su, Xianggui Wang, Wenru Su
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-01-01
Series:Fundamental Research
Subjects:
Single-cell RNA sequencing
Pregnancy
Maternal immune system
Aging
Immune tolerance
Dampened adaptive immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2667325822002813
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