DNA gains and losses in gigantic genomes do not track differences in transposable element-host silencing interactions

DNA gains and losses in gigantic genomes do not track differences in transposable element-host silencing interactions

Abstract Size evolution among gigantic genomes involves gain and loss of many gigabases of transposable elements (TEs), sequences that parasitize host genomes. Vertebrates suppress TEs using piRNA and KRAB-ZFP pathways. TEs and hosts coevolve in an arms race, where suppression strength reflects TE f...

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Main Authors: Jie Wang, Guangpu Zhang, Cheng Sun, Liming Chang, Yingyong Wang, Xin Yang, Guiying Chen, Michael W. Itgen, Ava Haley, Jiaxing Tang, Rachel Lockridge Mueller
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08127-3
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https://doi.org/10.1038/s42003-025-08127-3

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