Beyond the fever: shotgun metagenomic sequencing of stool unveils pathogenic players in HIV-infected children with non-malarial febrile illness

Beyond the fever: shotgun metagenomic sequencing of stool unveils pathogenic players in HIV-infected children with non-malarial febrile illness

Abstract Background Non-malarial febrile illnesses (NMFI) pose significant challenges in HIV-infected children, often leading to severe complications and increased morbidity. While traditional diagnostic approaches focus on specific pathogens, shotgun metagenomic sequencing offers a comprehensive to...

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Main Authors: Patricia Nabisubi, Stephen Kanyerezi, Grace Kebirungi, Ivan Sserwadda, Mike Nsubuga, Grace Kisitu, Patricia Ntege Nahirya, Bonny Mulindwa, George P. Akabwai, Sylvia Nantongo, Adeodata Kekitiinwa, Edgar Kigozi, Nsubuga Moses Luutu, Fred Ashaba Katabazi, Leymon Kalema, Andrew Katabalwa, Daudi Jjingo, Gerald Mboowa
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
Subjects:
Children
HIV-Infected
Non-malarial febrile illness
Shotgun metagenomic sequencing
Uganda
Online Access:https://doi.org/10.1186/s12879-025-10517-1
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https://doi.org/10.1186/s12879-025-10517-1

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