Transport of Alzheimer's associated amyloid-β catalyzed by P-glycoprotein.
P-glycoprotein (P-gp) is a critical membrane transporter in the blood brain barrier (BBB) and is implicated in Alzheimer's disease (AD). However, previous studies on the ability of P-gp to directly transport the Alzheimer's associated amyloid-β (Aβ) protein have produced contradictory resu...
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Main Authors: | James W McCormick, Lauren McCormick, Gang Chen, Pia D Vogel, John G Wise |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
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Series: | PLoS ONE |
Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0250371&type=printable |
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