Research progress on ferroptosis and PARP inhibitors in ovarian cancer: action mechanisms and resistance mechanisms

Ovarian cancer, a gynecologic malignancy with high mortality rates, faces persistent therapeutic challenges due to acquired resistance and frequent recurrence with conventional therapies. While poly (ADP-ribose) polymerase (PARP) inhibitors have primarily transformed clinical outcomes through the sy...

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Bibliographic Details
Main Authors: Jiqing Zhang, Dan Ouyang, Mu Liu, Yuting Xiang, Zhongjun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1598279/full
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