Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress

Abstract Background Many different stress signaling pathways converge in a common response: slowdown or arrest cell cycle in the G1 phase. The G1/S transition (called Start in budding yeast) is a key checkpoint controlled by positive and negative regulators. Among them, Whi7 and Whi5 are transcripti...

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Bibliographic Details
Main Authors: Mihai Spiridon-Bodi, Cristina Ros-Carrero, J. Carlos Igual, Mercè Gomar-Alba
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02027-z
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