Foamy monocytes and atherogenesis in mice with combined hyperlipidemia and effects of antisense knockdown of apoCIII

Foamy monocytes and atherogenesis in mice with combined hyperlipidemia and effects of antisense knockdown of apoCIII

Hypertriglyceridemia (HTG), particularly in combined hyperlipidemia, increases risk for atherosclerotic cardiovascular disease, but the underlying mechanisms remain incompletely understood. We sought to determine contributions of circulating monocytes to atherosclerosis associated with HTG in combin...

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Main Authors: Xueying Peng, Zeqin Lian, Veronica O'Brien, Jing Xiao, Benjamin A. Litchfield, Xiao-Yuan Dai Perrard, Lu Xu, Jing Ni, Aparna Mukherjee, Timothy Simmons, Henry Dong, Adam E. Mullick, Rosanne Crooke, Henry J. Pownall, Scott I. Simon, Christie M. Ballantyne, Huaizhu Wu
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
cholesterol
foam cells
inflammation
lipoproteins
monocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227525000239
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