Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview

Abstract Labor analgesia is increasingly widespread throughout the world with a rate ranging from 10 to 60%. The benefits regarding clinical and non-clinical maternal–fetal outcomes are currently discussed in international scientific literature. Even stage of labor needs a different and appropriate...

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Main Authors: Antonio Coviello, Carmine Iacovazzo, Maria Grazia Frigo, Marilena Ianniello, Dario Cirillo, Giuseppe Tierno, Andrea Uriel de Siena, Pasquale Buonanno, Giuseppe Servillo
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Anesthesia, Analgesia and Critical Care
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Online Access:https://doi.org/10.1186/s44158-025-00224-3
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author Antonio Coviello
Carmine Iacovazzo
Maria Grazia Frigo
Marilena Ianniello
Dario Cirillo
Giuseppe Tierno
Andrea Uriel de Siena
Pasquale Buonanno
Giuseppe Servillo
author_facet Antonio Coviello
Carmine Iacovazzo
Maria Grazia Frigo
Marilena Ianniello
Dario Cirillo
Giuseppe Tierno
Andrea Uriel de Siena
Pasquale Buonanno
Giuseppe Servillo
author_sort Antonio Coviello
collection DOAJ
description Abstract Labor analgesia is increasingly widespread throughout the world with a rate ranging from 10 to 60%. The benefits regarding clinical and non-clinical maternal–fetal outcomes are currently discussed in international scientific literature. Even stage of labor needs a different and appropriate approach to control the pain; however, different techniques are reported in literature. The following study intends to give a brief overview of the characteristics of the different neuraxial and non-neuraxial techniques currently available and the non-technical skills necessary for effective assistance to pregnant women, providing insights on the topic to understand critical issues at the same time. After bibliographic research since 2018 to 2023, many randomized controlled trials, literature reviews, systematic reviews, and metanalysis were evaluated to create this brief overview. The following pharmacological and non-pharmacological approaches were assessed: spinal techniques, such as epidural analgesia (EA), combined spinal-epidural (CSE), dural puncture epidural (DPE), and continuous spinal anesthesia (CSA); pharmacological administration of nitrous oxide (N2O) and systemic opioids (morphine, fentanyl, and pethidine); as the third one transcutaneous electric nerve stimulation (TENS), acupressure/acupuncture, aromatherapy, and breathing exercises. All the assessed approaches are relatively safe and effective, but the association of technical and non-technical skills is needed to improve the maternal and fetus outcome. More studies are needed to clarify what is the best approach to labor analgesia.
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spelling doaj-art-d589b387678a4019bbacf35a2e4498512025-02-02T12:47:26ZengBMCJournal of Anesthesia, Analgesia and Critical Care2731-37862025-01-015111210.1186/s44158-025-00224-3Technical aspects of neuraxial analgesia during labor and maternity care: an updated overviewAntonio Coviello0Carmine Iacovazzo1Maria Grazia Frigo2Marilena Ianniello3Dario Cirillo4Giuseppe Tierno5Andrea Uriel de Siena6Pasquale Buonanno7Giuseppe Servillo8Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”UOSD, Obstetric Anesthesia and ResuscitationDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”Abstract Labor analgesia is increasingly widespread throughout the world with a rate ranging from 10 to 60%. The benefits regarding clinical and non-clinical maternal–fetal outcomes are currently discussed in international scientific literature. Even stage of labor needs a different and appropriate approach to control the pain; however, different techniques are reported in literature. The following study intends to give a brief overview of the characteristics of the different neuraxial and non-neuraxial techniques currently available and the non-technical skills necessary for effective assistance to pregnant women, providing insights on the topic to understand critical issues at the same time. After bibliographic research since 2018 to 2023, many randomized controlled trials, literature reviews, systematic reviews, and metanalysis were evaluated to create this brief overview. The following pharmacological and non-pharmacological approaches were assessed: spinal techniques, such as epidural analgesia (EA), combined spinal-epidural (CSE), dural puncture epidural (DPE), and continuous spinal anesthesia (CSA); pharmacological administration of nitrous oxide (N2O) and systemic opioids (morphine, fentanyl, and pethidine); as the third one transcutaneous electric nerve stimulation (TENS), acupressure/acupuncture, aromatherapy, and breathing exercises. All the assessed approaches are relatively safe and effective, but the association of technical and non-technical skills is needed to improve the maternal and fetus outcome. More studies are needed to clarify what is the best approach to labor analgesia.https://doi.org/10.1186/s44158-025-00224-3Epidural analgesiaLabor analgesiaMaternal–fetal safetyLabor pain
spellingShingle Antonio Coviello
Carmine Iacovazzo
Maria Grazia Frigo
Marilena Ianniello
Dario Cirillo
Giuseppe Tierno
Andrea Uriel de Siena
Pasquale Buonanno
Giuseppe Servillo
Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview
Journal of Anesthesia, Analgesia and Critical Care
Epidural analgesia
Labor analgesia
Maternal–fetal safety
Labor pain
title Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview
title_full Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview
title_fullStr Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview
title_full_unstemmed Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview
title_short Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview
title_sort technical aspects of neuraxial analgesia during labor and maternity care an updated overview
topic Epidural analgesia
Labor analgesia
Maternal–fetal safety
Labor pain
url https://doi.org/10.1186/s44158-025-00224-3
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