Biochemical properties and substrate specificity of GOB-38 in Elizabethkingia anophelis

Biochemical properties and substrate specificity of GOB-38 in Elizabethkingia anophelis

Abstract The novel pathogen, Elizabethkingia anophelis, has gained attention due to its high mortality rates and drug resistance facilitated by its inherent metallo-β-lactamases (MBLs) genes. This study successfully identified and outlined the functions of the B3-Q MBLs variant, GOB-38, in a clinica...

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Bibliographic Details
Main Authors: Ren Liu, Yang Liu, Jiehui Qiu, Qun Ren, Chunping Wei, Dejin Pan, Jianglong Shi, Peng Liu, DanDan Wei, Tianxin Xiang, Na Cheng
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Metallo-β-lactamases
GOB-38
Antibiotic resistance
Elizabethkingia anophelis
Acinetobacter baumannii
Online Access:https://doi.org/10.1038/s41598-024-82748-2
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https://doi.org/10.1038/s41598-024-82748-2

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