Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB
Primary cardiac synovial sarcoma (PCSS) most commonly originates in the right atrium of the heart and is exceptionally rare. Although biomarkers of autoimmune diseases, such as antinuclear antibodies (ANAs), have been reported as potential indicators of certain tumors, the association between PCSS a...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1515233/full |
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| author | Yanmei Feng Chunxia Wu Jing Chi Linying Li Pu Wang Rui Guo |
| author_facet | Yanmei Feng Chunxia Wu Jing Chi Linying Li Pu Wang Rui Guo |
| author_sort | Yanmei Feng |
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| description | Primary cardiac synovial sarcoma (PCSS) most commonly originates in the right atrium of the heart and is exceptionally rare. Although biomarkers of autoimmune diseases, such as antinuclear antibodies (ANAs), have been reported as potential indicators of certain tumors, the association between PCSS and ANAs remains unclear. Herein, we describe a case of pleural effusion that was initially considered to be due to connective tissue disease (CTD) but was finally diagnosed as PCSS through endobronchial ultrasound-guided transbronchial mediastinum biopsy (EBUS-TBMB). Clinicians need to update their knowledge regarding the potential association between PCSS and ANAs. This case report also emphasizes the importance of EBUS-TBMB, under the guidance of positron emission tomography/computed tomography (PET/CT), in the diagnosis of this rare tumor in an unusual location. |
| format | Article |
| id | doaj-art-d5529cf06a2e4176bc9996e70744e10f |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-d5529cf06a2e4176bc9996e70744e10f2025-02-05T07:32:51ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-02-011210.3389/fmed.2025.15152331515233Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMBYanmei Feng0Chunxia Wu1Jing Chi2Linying Li3Pu Wang4Rui Guo5Department of Respiratory Medicine, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaCenter for Excellence in Brain Science and Intelligence Technology (CEBSIT), Institute of Neuroscience(ION), Chinese Academy of Sciences, Beijing, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Emergency Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaPrimary cardiac synovial sarcoma (PCSS) most commonly originates in the right atrium of the heart and is exceptionally rare. Although biomarkers of autoimmune diseases, such as antinuclear antibodies (ANAs), have been reported as potential indicators of certain tumors, the association between PCSS and ANAs remains unclear. Herein, we describe a case of pleural effusion that was initially considered to be due to connective tissue disease (CTD) but was finally diagnosed as PCSS through endobronchial ultrasound-guided transbronchial mediastinum biopsy (EBUS-TBMB). Clinicians need to update their knowledge regarding the potential association between PCSS and ANAs. This case report also emphasizes the importance of EBUS-TBMB, under the guidance of positron emission tomography/computed tomography (PET/CT), in the diagnosis of this rare tumor in an unusual location.https://www.frontiersin.org/articles/10.3389/fmed.2025.1515233/fullprimary cardiac synovial sarcomaantinuclear antibodiespleural effusionconnective tissue diseaseEBUS-TBMB |
| spellingShingle | Yanmei Feng Chunxia Wu Jing Chi Linying Li Pu Wang Rui Guo Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB Frontiers in Medicine primary cardiac synovial sarcoma antinuclear antibodies pleural effusion connective tissue disease EBUS-TBMB |
| title | Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB |
| title_full | Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB |
| title_fullStr | Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB |
| title_full_unstemmed | Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB |
| title_short | Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB |
| title_sort | case report primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by ebus tbmb |
| topic | primary cardiac synovial sarcoma antinuclear antibodies pleural effusion connective tissue disease EBUS-TBMB |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1515233/full |
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