S1P receptor modulators affect the toxicity of amyloid β oligomers in microglial and neuronal cells

S1P receptor modulators affect the toxicity of amyloid β oligomers in microglial and neuronal cells

A large body of evidence has shown that the amyloid b peptide oligomers (Abo) are predominantly responsible for the neurodegeneration/cognitive impairments in Alzheimer’s disease (AD). Abo cause mitochondrial dysfunctions leading to an imbalance between pro- and antiapoptotic proteins and finally to...

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Bibliographic Details
Main Authors: Iga Wieczorek, Robert P. Strosznajder
Format: Article
Language:English
Published: Termedia Publishing House 2024-12-01
Series:Folia Neuropathologica
Subjects:
alzheimer’s disease
amyloid b oligomers
sphingosine-1-phosphate (s1p)
s1p receptors
modulators of s1p receptors
Online Access:https://www.termedia.pl/S1P-receptor-modulators-affect-the-toxicity-of-amyloid-oligomers-in-microglial-and-neuronal-cells,20,55299,1,1.html
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https://www.termedia.pl/S1P-receptor-modulators-affect-the-toxicity-of-amyloid-oligomers-in-microglial-and-neuronal-cells,20,55299,1,1.html

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