Bile acid accumulation induced by miR-122 deficiency in liver parenchyma promotes cancer cell growth in hepatocellular carcinoma

Liver is the central player in maintaining metabolic homeostasis of bile acids (BAs), but how BA is tightly controlled is still largely unknown, and the role of BAs in the development of hepatocellular carcinoma (HCC) remains controversial. Here, we discovered that elevated hepatic BAs were associat...

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Bibliographic Details
Main Authors: Jia-Hui Huang, Yi-Hang Li, Juan-Zhen Hong, Ruo-Nan Li, Ruizhi Wang, Zi-Qi Chen, Song-Yang Li, Ying-Lei Chi, Jin-Yu Huang, Ying Zhu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Therapy: Nucleic Acids
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Online Access:http://www.sciencedirect.com/science/article/pii/S2162253125001143
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