Immunopathological Dysregulation in Acute Myeloid Leukemia: The Impact of T-bet, RORγt, and FOXP3 on Disease Dynamics

Immunopathological Dysregulation in Acute Myeloid Leukemia: The Impact of T-bet, RORγt, and FOXP3 on Disease Dynamics

The etiology of acute myeloid leukemia (AML) is complex, including genetic and environmental abnormalities. The immune system anomalies play an essential role in the process of leukemogenesis. However, the immunopathological factors, including abnormal T helper (Th) subsets, contributing to the init...

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Bibliographic Details
Main Authors: Amira M. Mohamed Mohy El-Din, Buthayna Ahmad AlShaarawy, Eman Zaghloul Kandeel, Dalia Mahmoud AlDewi, Lobna Abdel Azeem Refaat, Borros Arneth, Hussein Sabit
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
patterns
T helper
transcription factors
flowcytometry
acute myeloid leukemia
Online Access:https://www.mdpi.com/2073-4409/14/7/528
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