Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy
Objective. The aim of this study was to investigate the extent of placental lesions associated with blood pressure (BP) levels in pregnancies complicated by hypertension. Methods. 55 singleton pregnancies complicated by mild hypertension were recruited and compared to 55 pregnancies complicated by s...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2012/684083 |
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| author | Vassiliki Krielessi Nikos Papantoniou Ioannis Papageorgiou Ioannis Chatzipapas Efstathios Manios Nikos Zakopoulos Aris Antsaklis |
| author_facet | Vassiliki Krielessi Nikos Papantoniou Ioannis Papageorgiou Ioannis Chatzipapas Efstathios Manios Nikos Zakopoulos Aris Antsaklis |
| author_sort | Vassiliki Krielessi |
| collection | DOAJ |
| description | Objective. The aim of this study was to investigate the extent of placental lesions associated with blood pressure (BP) levels in pregnancies complicated by hypertension. Methods. 55 singleton pregnancies complicated by mild hypertension were recruited and compared to 55 pregnancies complicated by severe hypertension. The histological assessment was carried out with regard to the following aspects: vessels number/field of vision, infarction, villous fibrinoid necrosis, villous hypermaturity, avascular villi, calcifications, lymphohistiocytic villitis, and thickened vessels. Statistical analysis was performed by SPSS. Results. All placental lesions were observed more often in the severe hypertension group. Vessels number was significantly decreased, and infarction and villous fibrinoid necrosis were significantly increased in the placentas of the severe hypertension group compared to the mild hypertension group (𝑃<0.001). Conclusion. This study supports that the extent of placental lesions in hypertensive pregnancies is correlated with hypertension level and so highlights blood pressure level as a mirror of placental function. |
| format | Article |
| id | doaj-art-d4fc74a377b0483e8890dc89f71969e7 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-d4fc74a377b0483e8890dc89f71969e72025-02-03T01:20:46ZengWileyObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/684083684083Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in PregnancyVassiliki Krielessi0Nikos Papantoniou1Ioannis Papageorgiou2Ioannis Chatzipapas3Efstathios Manios4Nikos Zakopoulos5Aris Antsaklis6First Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceFirst Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceFirst Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceFirst Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceFirst Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceFirst Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceFirst Department of Obstetrics and Gynecology, University of Athens, “Alexandra” Hospital, Lourou and Vasilissis Sofias, 11528 Athens, GreeceObjective. The aim of this study was to investigate the extent of placental lesions associated with blood pressure (BP) levels in pregnancies complicated by hypertension. Methods. 55 singleton pregnancies complicated by mild hypertension were recruited and compared to 55 pregnancies complicated by severe hypertension. The histological assessment was carried out with regard to the following aspects: vessels number/field of vision, infarction, villous fibrinoid necrosis, villous hypermaturity, avascular villi, calcifications, lymphohistiocytic villitis, and thickened vessels. Statistical analysis was performed by SPSS. Results. All placental lesions were observed more often in the severe hypertension group. Vessels number was significantly decreased, and infarction and villous fibrinoid necrosis were significantly increased in the placentas of the severe hypertension group compared to the mild hypertension group (𝑃<0.001). Conclusion. This study supports that the extent of placental lesions in hypertensive pregnancies is correlated with hypertension level and so highlights blood pressure level as a mirror of placental function.http://dx.doi.org/10.1155/2012/684083 |
| spellingShingle | Vassiliki Krielessi Nikos Papantoniou Ioannis Papageorgiou Ioannis Chatzipapas Efstathios Manios Nikos Zakopoulos Aris Antsaklis Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy Obstetrics and Gynecology International |
| title | Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy |
| title_full | Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy |
| title_fullStr | Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy |
| title_full_unstemmed | Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy |
| title_short | Placental Pathology and Blood Pressure’s Level in Women with Hypertensive Disorders in Pregnancy |
| title_sort | placental pathology and blood pressure s level in women with hypertensive disorders in pregnancy |
| url | http://dx.doi.org/10.1155/2012/684083 |
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