ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA

Background: Diffusion Weighted Imaging and Diffusion Tensor Imaging is an advanced technique in MRI that shows the diffusion in brain of ischemic stroke disease. Diffusion Weighted Imaging (DWI) shows the lesions without gadolinium contrast agent and produce Apparent Diffusion Coefficient values. Wh...

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Main Authors: Ali Mustofa, Anggraini Dwi Sensusiati, Muhaimin Muhaimin, Sri Andreani Utomo, Risalatul Latifah
Format: Article
Language:English
Published: Universitas Airlangga 2019-05-01
Series:Journal of Vocational Health Studies
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Online Access:https://e-journal.unair.ac.id/JVHS/article/view/13125
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author Ali Mustofa
Anggraini Dwi Sensusiati
Muhaimin Muhaimin
Sri Andreani Utomo
Risalatul Latifah
author_facet Ali Mustofa
Anggraini Dwi Sensusiati
Muhaimin Muhaimin
Sri Andreani Utomo
Risalatul Latifah
author_sort Ali Mustofa
collection DOAJ
description Background: Diffusion Weighted Imaging and Diffusion Tensor Imaging is an advanced technique in MRI that shows the diffusion in brain of ischemic stroke disease. Diffusion Weighted Imaging (DWI) shows the lesions without gadolinium contrast agent and produce Apparent Diffusion Coefficient values. Whereas, Diffusion Tensor Imaging (DTI) shows connectivity’s of central nervous system that cannot be seen by using conventional MRI. Diffusion Tensor Imaging produces Fractional Anisotropy values. Purpose:This study has aim to analyze the Apparent Diffusion Coefficient values and Fractional Anisotropy values in Stroke Ischemic disease. Methods: Total samples used are 14 samples, consist of 7 (50%) man and 7 (50%) woman with ischemic stroke disease. Each sample deals by Diffusion Weighted Imaging and Diffusion Tensor Imaging sequences. The Region of Interest (ROI) is placed in ischemic stroke lesions and contra lateral side of lesions. Results: The result shows that 9 samples of brain tissue lesions located in the right side and 5 samples in the left side. Right lesions have the average ADC stroke: 0.001748; normal ADC: 0.000954; FA stroke: 0.144522; and normal FA: 0.426111. While, left lesions have the average ADC strokes 0.000979; normal ADC: 0.000835; FA stroke: 0.2556; and normal FA 0.4324. Conclusion: So, the conclusion of this study is Apparent Diffusion Coefficient (ADC) values in case of ischemic stroke can decreases or increases depend on the age of stroke. While, the Fractional Anisotropy (FA) values will decrease without being affected by age of stroke.
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spelling doaj-art-d4f07e29abda47569cfed810e3d930ad2025-02-02T11:19:52ZengUniversitas AirlanggaJournal of Vocational Health Studies2580-71612580-717X2019-05-012310711110.20473/jvhs.V2.I3.2019.107-1116664ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLAAli Mustofa0Anggraini Dwi Sensusiati1Muhaimin Muhaimin2Sri Andreani Utomo3Risalatul Latifah4Islamic Hospital, Jombang-IndonesiaDepartement of Radiology, Universitas Airlangga Hospital, Surabaya-IndonesiaDepartment of Health, Faculty Of Vocational Health Studies, Universitas Airlangga, Surabaya-IndonesiaDepartment of Radiology, General Hospital Dr. Soetomo, Surabaya-IndonesiaDepartment of Health, Faculty Of Vocational Health Studies, Universitas Airlangga, Surabaya-IndonesiaBackground: Diffusion Weighted Imaging and Diffusion Tensor Imaging is an advanced technique in MRI that shows the diffusion in brain of ischemic stroke disease. Diffusion Weighted Imaging (DWI) shows the lesions without gadolinium contrast agent and produce Apparent Diffusion Coefficient values. Whereas, Diffusion Tensor Imaging (DTI) shows connectivity’s of central nervous system that cannot be seen by using conventional MRI. Diffusion Tensor Imaging produces Fractional Anisotropy values. Purpose:This study has aim to analyze the Apparent Diffusion Coefficient values and Fractional Anisotropy values in Stroke Ischemic disease. Methods: Total samples used are 14 samples, consist of 7 (50%) man and 7 (50%) woman with ischemic stroke disease. Each sample deals by Diffusion Weighted Imaging and Diffusion Tensor Imaging sequences. The Region of Interest (ROI) is placed in ischemic stroke lesions and contra lateral side of lesions. Results: The result shows that 9 samples of brain tissue lesions located in the right side and 5 samples in the left side. Right lesions have the average ADC stroke: 0.001748; normal ADC: 0.000954; FA stroke: 0.144522; and normal FA: 0.426111. While, left lesions have the average ADC strokes 0.000979; normal ADC: 0.000835; FA stroke: 0.2556; and normal FA 0.4324. Conclusion: So, the conclusion of this study is Apparent Diffusion Coefficient (ADC) values in case of ischemic stroke can decreases or increases depend on the age of stroke. While, the Fractional Anisotropy (FA) values will decrease without being affected by age of stroke.https://e-journal.unair.ac.id/JVHS/article/view/13125diffusion weighted imagingdiffusion tensor imagingapparent diffusion coefficientfractional anisotropyischemic stroke
spellingShingle Ali Mustofa
Anggraini Dwi Sensusiati
Muhaimin Muhaimin
Sri Andreani Utomo
Risalatul Latifah
ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA
Journal of Vocational Health Studies
diffusion weighted imaging
diffusion tensor imaging
apparent diffusion coefficient
fractional anisotropy
ischemic stroke
title ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA
title_full ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA
title_fullStr ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA
title_full_unstemmed ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA
title_short ANALYSIS OF FRACTIONAL ANISOTROPY (FA) VALUES AND APPARENT DIFFUSION COEFFICIENT (ADC) VALUES IN ISCHEMIC STROKE DISEASES OF MRI GE 3 TESLA
title_sort analysis of fractional anisotropy fa values and apparent diffusion coefficient adc values in ischemic stroke diseases of mri ge 3 tesla
topic diffusion weighted imaging
diffusion tensor imaging
apparent diffusion coefficient
fractional anisotropy
ischemic stroke
url https://e-journal.unair.ac.id/JVHS/article/view/13125
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