Spironolactone and metformin combination therapy as a potential non-hormonal treatment for management of hyperandrogenic symptoms of polycystic ovarian syndrome

Spironolactone and metformin combination therapy as a potential non-hormonal treatment for management of hyperandrogenic symptoms of polycystic ovarian syndrome

Introduction: Polycystic ovarian syndrome (PCOS) is one of the most common endocrinological conditions in women of child-bearing age.1 It is characterised by symptoms of oligo- or anovulation, hyperandrogenism and polycystic ovarian morphology.2 Current mainstay treatment for PCOS involves off-label...

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Main Authors: Irene Karderinis, Yangxinrui Ma, Telma Viveiros, Neha Deshpande, Bassel Watter, Vikram Talaulikar
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Clinical Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S1470211825001794
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