STUDY OF THE EFFECT OF LOMUSTIN ON HER2-POSITIVE BREAST CANCER IN FVB/N HER-2 TRANSGENIC MICE

STUDY OF THE EFFECT OF LOMUSTIN ON HER2-POSITIVE BREAST CANCER IN FVB/N HER-2 TRANSGENIC MICE

Because of the high risk of brain metastases from HER2-positive breast cancer, the study of the anticancer activity of drugs used to treat brain tumors, in particular lomustine, is of great importance. In the FVB/N Her-2 transgenic mice bearing HER2-positive breast cancer (BC HER2+), a single oral a...

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Main Authors: A. N. Stukov, S. F. Vershinina, N. A. Koziavin, T. Yu. Semiglazova, L. V. Filatova, D. Kh. Latipova, A. O. Ivantsov, V. G. Bespalov, A. L. Semenov, O. A. Belyaeva, G. S. Kireeva, V. A. Alexandrov, G. V. Tochilnikov, I. N. Vasilyeva, M. A. Maydin, M. L. Tyndyk, S. S. Kruglov, G. A. Yanus, V. N. Yurova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2019-11-01
Series:Сибирский онкологический журнал
Subjects:
her2-positive breast cancer
her2 transgenic fvb/n mice
lomustine
intracranial tumor
tumor growth index
Online Access:https://www.siboncoj.ru/jour/article/view/1188
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