Comparative and functional genomic analysis of foreign DNA defense mechanisms in Enterococcus faecium

Comparative and functional genomic analysis of foreign DNA defense mechanisms in Enterococcus faecium

ABSTRACT Enterococcus faecium is notoriously difficult to study genetically due to the poor understanding of barriers preventing foreign DNA uptake, such as the proteins that modify type I restriction modification (RM) system activity. Here, we compared E. faecium repertoires of the HsdS specificity...

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Bibliographic Details
Main Authors: Alexandra L. Krause, Louise M. Judd, Ryan Wick, Timothy P. Stinear, Andrew H. Buultjens, Ian R. Monk
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
Enterococcus faecium
genomics
DNA defense mechanisms
restriction modification system
hsdS
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00289-25
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https://journals.asm.org/doi/10.1128/spectrum.00289-25

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