The fitness cost and benefit of phase‐separated protein deposits

Abstract Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less compartments for many cellular processes. What are the fitness costs and benefits of forming such deposits in different conditions?...

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Bibliographic Details
Main Authors: Natalia Sanchez de Groot, Marc Torrent Burgas, Charles NJ Ravarani, Ala Trusina, Salvador Ventura, M Madan Babu
Format: Article
Language:English
Published: Springer Nature 2019-04-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20178075
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